Carlos H. G. C. D. Abreu

Assistant Researcher & Immunologist
Porto, PT.

About

Highly accomplished Assistant Researcher with over a decade of experience in advanced immunology, focusing on host-pathogen interactions, T-cell biology, and vaccine development. Expert in securing competitive funding, leading complex research projects, and publishing high-impact scientific findings in top-tier journals. Driven to leverage deep immunological expertise to uncover novel therapeutic targets and advance global health initiatives.

Work

University of Porto, Faculty of Medicine (FMUP)
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Assistant Researcher

Porto, Porto, Portugal

Summary

Leading independent research focused on host-pathogen interactions and T-cell immunology, contributing to advanced understanding of immune responses and disease mechanisms.

Highlights

Secured highly competitive FCT Scientific Employment Stimulus funding in 2021, enabling the establishment and independent direction of a novel research line.

Published multiple peer-reviewed articles in high-impact immunology journals, advancing knowledge in T-cell differentiation and host defense strategies.

Managed and directed complex research projects, overseeing experimental design, data analysis, and scientific reporting for critical studies.

Mentored and supervised junior researchers, PhD students, and master's candidates, fostering their scientific development and project execution.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
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Postdoctoral Researcher

Porto, Porto, Portugal

Summary

Conducted advanced postdoctoral research in immunology, investigating T-cell responses to pathogens and contributing to vaccine development initiatives.

Highlights

Investigated T-cell responses to various pathogens, leading to a deeper understanding of immune protective mechanisms and immunopathology.

Developed and optimized novel immunological assays and experimental models, enhancing research capabilities and data precision.

Collaborated effectively with multidisciplinary teams on several projects, contributing critical immunological expertise to achieve research objectives.

Contributed significantly to grant applications and scientific reports, securing resources and disseminating research outcomes to the scientific community.

National Institute for Medical Research (NIMR), MRC
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Postdoctoral Researcher

London, England, United Kingdom of Great Britain and Northern Ireland

Summary

Performed pioneering postdoctoral research on T-cell immunology and host-pathogen interactions at a world-renowned medical research institute.

Highlights

Executed in-depth studies on T-cell activation, differentiation, and memory formation in the context of infectious diseases, yielding significant insights.

Authored and co-authored multiple original research articles published in high-impact scientific journals, influencing the field of immunology.

Mastered a diverse array of advanced laboratory techniques, including flow cytometry, cell culture, and molecular biology methods, to drive experimental success.

Presented research findings at international conferences and seminars, effectively communicating complex scientific concepts to global audiences.

Education

Universidade do Porto
Porto, Porto, Portugal

PhD

Biomedical Sciences (Immunology)

Grade: Not specified

Courses

Doctoral research focused on T-cell responses in infectious diseases, culminating in a successful thesis defense.

Universidade do Porto
Porto, Porto, Portugal

Licenciatura (BSc equivalent)

Biology

Grade: Not specified

Courses

Comprehensive coursework in General Biology, Microbiology, Genetics, and Cell Biology, providing a strong scientific foundation.

Awards

FCT Scientific Employment Stimulus

Awarded By

Fundação para a Ciência e a Tecnologia (FCT)

Awarded highly competitive national funding to support independent research as an Assistant Researcher, recognizing significant scientific potential and contributions.

Publications

T-cell fate and function in malaria: from infection to immunity

Published by

Frontiers in Immunology

Summary

Comprehensive review article summarizing the current understanding of T-cell roles in malaria immunity, highlighting key research gaps and future directions for vaccine and therapeutic development.

Targeting the CD161-CLEC2D axis for therapeutic intervention in inflammatory diseases

Published by

Journal of Autoimmunity

Summary

Original research demonstrating a novel therapeutic target for inflammatory diseases through modulation of the CD161-CLEC2D pathway, with implications for autoimmune conditions.

Distinct roles for IL-17-producing T cells in host defense and immunopathology

Published by

Nature Immunology

Summary

Definitive study elucidating the dual roles of IL-17-producing T cells in both protective immunity against pathogens and their contribution to disease pathogenesis, impacting therapeutic strategies.

Early life exposure to environmental factors shapes the developing immune system

Published by

Immunity

Summary

Groundbreaking research demonstrating how environmental exposures during early life critically influence the development and long-term function of the immune system.

Languages

Portuguese
English

Skills

Immunology

T-cell Biology, Host-Pathogen Interactions, Immune Responses, Vaccine Development, Immunopathology, Autoimmunity, Infectious Diseases, Flow Cytometry, Cell Culture, ELISA.

Research & Development

Experimental Design, Data Analysis, Scientific Writing, Grant Writing, Project Management, Preclinical Research, Peer Review, Mentorship.

Molecular Biology

PCR, Western Blot, Gene Expression Analysis, DNA/RNA Isolation.

Microbiology & Parasitology

Bacteriology, Virology, Malaria Research, Infectious Agents.